mc2-CMX

Candidate Overview

The mc2-CMX vaccine is a live attenuated vaccine that was developed using M. tuberculosis Ag85, MPT-51 and HSP-x to generate a fusion protein called CMX. The nucleotide sequences corresponding to epitopes 85 to 159 bp of Ag85C and 91 to 112 bp of MPT51 and HSP-x. The gene sequence was inserted in the genome of Mycobacterium smegmatis. This vaccine is formulated in PBS Tween containing 10-7 CFU.

Additional Immunologic Response Information