Ad5Ag85A*

Ad5Ag85A is a human adenovirus serotype 5-vectored vaccine expressing Antigen 85A (Ag85A). This vaccine is delivered by the inhaled aerosol route.

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TB/FLU-05E

TB/FLU-05E is a mucosal TB vaccine candidate based on recombinant attenuated influenza vector (Flu/THSP) co-expressing truncated NS1 protein NS1(1–124) and a full-length TB10.4 and HspX proteins of M.tb within an NS1 protein open reading frame. Vaccine formulation: Liquid nasal spray.

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BCG (Travel vaccine)*

The purpose of this trial (TIPI Trial), is to find out if a single dose of pre-travel vaccination with BCG can lessen tuberculosis (TB) infection by producing an immune response when given to adults traveling to countries with a high burden of TB. BCG (Tokyo 172), supplied by Japan BCG Lab, will be compared with…

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ChAdOx1.85A+MVA85A*

ChAdOx1.85A is a simian adenoviral vector expressing Antigen 85A. MVA85A is a modified vaccinia virus Ankara expressing Antigen 85A. The target route of administration for ChAdOx1.85A is aerosol, and intramuscular for MVA85A.

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DAR-901^

DAR-901 is an inactivated whole cell vaccine derived from a non-tuberculous mycobacterium and represents a scalable manufacturing process for SRL172.

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