Lm::Mtb9Ag

This TB vaccine candidate comprises a live attenuated Listeria monocytogenes vector with two major virulence gene deletions and a T-cell immunity enhancing mutation (Lm ΔactA ΔinlB prfA*) that expresses nine M. tuberculosis immunoprotective proteins (Mpt64, TB10.4, ESAT-6, CFP10, Ag85B, EsxN, PPE68, EspA, and TB8.4 – four absent from BCG) from two chromosomal fusion protein expression…

Read More

BCGΔBCG1419c

This is a second-generation version of BCGΔBCG1419c, devoid of antibiotic markers. It is based on BCG Pasteur ATCC 35734.

Read More