rAd-Rv2299c
Candidate Overview
rAd-Rv2299c is a chimpanzee adenovirus-vectored vaccine expressing Rv2299c. Constructed using pRSK17 shuttle plasmid, packaged in HEK293A cells, and purified by cesium chloride density centrifugation. Formulated for intranasal inhalation at 1×10⁸ PFU/50 μL PBS. The platform exhibits low human seroprevalence with trained immunity induction in DCs. No exogenous adjuvants.